蔡宗苇

      蔡宗苇,博士,教授,博士生导师。1982年厦门大学化学系获得学士学位,1990年在德国University of Marburg获得博士学位,1991-1994在美国University of Nebraska 质谱研究中心从事博士后研究。1994-1996在美国University of Nebraska水质中心任助理教授,2001年受聘于香港浸会大学,现为香港浸会大学化学系教授,二恶英分析实验室主任。蔡宗苇教授是质谱分析专家,从事质谱的基础理论和应用研究,特别善长于高分辨质谱、GC-MS、LC-MS、CE-MS及其在环境、生物、药物和痕量有机污染物分析方面的应用研究。蔡教授2003年获得国家杰出青年基金,已在国际著名刊物上发表40多篇SCI论文,获得的科学研究基金近千万元,在生物质谱研究领域取得了突出的成绩。

Educational Background

    * B.Sc., Xiamen University, China
    * Ph.D., Marburg University, Germany
    * Postdoctoral: University of Nebraska-Lincoln, USA

Professional Appointments
    * Director of Dioxin Analysis Laboratory
    * Associate Director of The Joint Institute of Environmental Sciences of Hong Kong Baptist University and The Research Center for Eco-Environmental Sciences, The Chinese Academy of Sciences

Current Research Interests

    * Fundamentals and applications of mass spectrometry;
    * high resolution mass spectrometry;
    * Nanospray ESI-MS; GC-, LC- and CE-MS for environmental, biological, pharmaceutical and Chinese medicinal analyses;
    * trace analysis of dioxins and persistent organic pollutants.

Selected Publications

   1. Ning Liu, Wenjun Song, Pui Wang, Kim-Chung Lee, Zongwei Cai, Honglin Chen, "Identification of Unusual Truncated Forms of Nucleocapsid Protein in MDCK Cells Infected by Avian Influenza Virus (H9N2)", Proteomics, 10, 1875-1879 (2010).
   2. Shuhai Lin, Wan Chan, Jinhua Li and Zongwei Cai, "Liquid chromatography/mass spectrometry for investigating the biochemical effects induced by aristolochic acid in rats: the plasma metabolome", Rapid Commun. Mass Spectrom., 24, 1312-1318 (2010).
   3. Minghua Lu, Lan Zhang, Xin Li, Qiaomei Lu, Guonan Chen, Zongwei Cai, "A new method for the analysis of β2-agonists in human urine by pressure-assisted capillary electrochromatography coupled with electrospray ionization-mass spectrometry using a silica-based monolithic column", Talanta, 81, 1655-1661 (2010).
   4. Lin Guo, Hao Yue, Zongwei Cai, "A novel pre-column fluorescent derivatization method for the sensitive determination of aristolochic acids in medicinal herbs by high-performance liquid chromatography with fluorescence detection", J. of Pharmaceutical and Biomedical Analysis, 53, 37-42 (2010).
   5. Tianxiu Qian, Zongwei Cai, "Biotransformation of ginsenosides Rb1, Rg3 and Rh2 in rat gastrointestinal tracts", Chinese Medicine, 5, 19-26 (2010).
   6. Ning Liu, Genyan Huang, Yi Guan, Kimchung Lee, Honglin Chen, Zongwei Cai, “Mutations in Influenza Virus Replication and Transcription: Detection of Amino Acid Substitutions in Hemagglutinin of an Avian Influenza Virus (H1N1)”, FASEB Journal, 23, 3377-3382 (2009).
   7. Jun Wang, Tao Lin, Jiaping Lai, M.S. Yang, Zongwei Cai, “Analysis of Adenosine Phosphates in HepG-2 Cell by a HPLC-ESI-MS System with Porous Graphitic Carbon as Stationary Phase”, J. Chromatogr. B, 877, 2019-2024 (2009).
   8. Jinhua Li, Wan Chan, Zongwei Cai, “On-line CE-ESI-MS Analysis of Urinary Porphyrins”, Electrophoresis, 30, 1790-1797 (2009).
   9. Ning Liu, Wan Chan, Kim-Chung Lee, Zongwei Cai , “A Method to Enhance a1 Ions and Application for Peptide Sequencing and Protein Identification”, J. Am. Soc. Mass Spectrom., 20, 1214-1223 (2009).
  10. Ning Liu, Kim-Chung Lee, Wenjun Song, Pui Wang, Honglin Chen, Zongwei Cai, “Identification of Amino Acid Substitutions in Mutated Peptides of Nucleoprotein from Avian Influenza Virus”, Talanta, 78, 1492-1496 (2009).
  11. Wan Chan, Wing Tat Poon, Yan-Wo Chan, King-Yi Wan, Zongwei Cai, “A New Aproach for the Sensitive Determination of DNA Adduct of Aristolochic Acid II by Using HPLC with Fluorescence Detection”, J. Chromatogr. B, 877, 848-852 (2009).
  12. Hao Yue, Wan Chan, Lin Guo, Zongwei Cai, “Determination of Aristolochic Acid I in Rat Urine and Plasma by HPLC with Fluorescence Detection”, J. Chromatogr. B, 877, 995-999 (2009).
 

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